A steel building is rarely governed by one load acting alone. Permanent weight, occupancy, wind, snow, seismic effects, cranes, temperature, and other actions can occur in different directions and at different levels of intensity.
Load combinations are the code-defined arrangements used to evaluate these concurrent effects. They apply factors and compatibility rules so that engineers check credible unfavorable situations without assuming that every variable action reaches its maximum value everywhere at the same moment.
This article is the integration hub for the Loads Cluster. It explains the logic and principal design frameworks, not the project-specific equations required by any one code edition.